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In a study out of Johns Hopkins University that was published in the December 2014 issue of the Journal of Molecular Biology, researchers found that the amount of mitochondrial DNA found in blood directly correlated with frailty and longevity 10-15 years before symptoms appeared. Patients were followed over 10-20 years looking at the amount of mitochondrial DNA...

Fatigue is a problem for almost everyone at some time during their life.  Four main causes are malnutrition, pollution, stress, and damage. Genetics could also play a role.  Dr. Saputo and Dr. Kunin discuss fatigue at the cellular level and the lack of energy production (the cellular production of ATP) and the miracle of mitochondria.