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There is an increased risk for hypertension, heart attacks, congestive heart failure, and bone fractures associated with the use of Avandia. It inhibits the formation of new bone and increases of bone breakdown.        

Lately there have been reports about the bisphosphonates used to treat osteoporosis, are causing fractures of the femur and other bones in the body.  The drugs most commonly prescribed are Actonel, Fosamax, Reclast, and Boniva to name a few.  These drugs are powerful and cause dramatic changes in bone physiology.  It may be true that these drugs...

  The little understood protein, osteocalcin, plays a significant role in the strength of our bones. It is made by osteoblasts, the cells that lay down new bone. Osteocalcin cannot be absorbed into bone in the absence of adequate vitamin K, which comes from eating green leafy vegetables. This is a particular problem in people taking Coumadin for protection...