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  Biochemical signs of Alzheimer's Disease are reflected by the brain's limited capacity to metabolize glucose occur 20 years prior to the memory and cognitive defects we associate with the clinical disease. A shortage of ATP (energy) in the brain eventually leads to an electrical brown out manifested by recent memory loss and cognitive defects...

According to an article published in the November 2013 issue of the medical journal, Nature, glucose regulation is only 50% related to the action of insulin. The other 50% is regulated through a mechanism called "glucose effectiveness" that originates in the hypothalamus of the brain. Glucose effectiveness is an unrelated separate mechanism from...