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With too little or too much iron the end result is a disaster. Iron deficiency in pregnancy causes mental retardation and iron excess in adults predisposes to premature aging. Five percent of the population has the gene for iron overload.      

  According to a study in the July 2012 issue of the Canadian Medical Association Journal, iron supplementation reduced fatigue by about 50% in women with low iron but without anemia. When ferritin levels are below 50 and women with fatigue are supplemented with just 80 mg of iron per day over 12 weeks, their fatigue decreased and their iron levels increased...

  According to the December 2012 issue of PLOS ONE, Iron plays a key role in metabolism that leads to bacteria and human beings competing to prevent the other from obtaining it. Bacteria are obligated to acquire iron to gain foothold to grow in host tissues. Cancer cells also sequester iron more effectively than normal cells. This is one of the reasons...

  Iron storage disease, or hemochromatosis, affects 10-15% of the population, and perhaps even more if you know how to diagnose it. Iron overload increases free radical damage via the Fenton reaction. Hepcidin is a hormone that regulates iron levels by increasing the absorption of iron. The is new research showing that at least experimentally it is possible...